箴言
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在科学上没有平坦的大道,只有那些不畏艰险沿着陡峭山路攀登的人,才有希望达到光辉的顶点。
----马克思
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合作研究
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请有兴趣的研究组联系我们。欢迎任何形式的合作，尤其是在自组装、水凝胶以及生物医药等方向的合作。
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请有兴趣的研究组联系我们。欢迎任何形式的合作，尤其是在自组装、水凝胶以及生物医药等方向的合作。
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研究成果
50. T10 Polyhedral Oligomeric Silsesquioxane-Based Shape Amphiphiles with Diverse Head Functionalities via “Click” Chemistry. ACS Macro Lett., 2014, 3, 900–905
发布时间:2016-04-27
Feng, X.; Zhu, S.; Yue, K.; Su, H.; Guo, K.; Wesdemiotis, C.; Zhang, W.-B.;* Cheng, S.Z.D.;* Li, Y.* T10 Polyhedral Oligomeric Silsesquioxane-Based Shape Amphiphiles with Diverse Head Functionalities via “Click” Chemistry ACS Macro Lett., 2014, 3, 900–905. [Link] [PDF]
Abstract
Head diversification of shape amphiphiles not only broadens the scope of supramolecular engineering for new self-organizing materials but also facilitates their potential applications in high technologies. In this letter, T10 azido-functionalized polyhedral oligomeric silsesquioxane (POSS) nanoparticle was used to construct new shape amphiphiles via sequential “click” chemistry for addressing two issues: (1) new symmetry of T10 POSS head could enrich the self-assembly behaviors of shape amphiphiles, and (2) copper-catalyzed azide–alkyne cycloaddition (CuAAC)-based head functionalization strategy allows the introduction of diverse functionalities onto POSS heads, including bulky ligands (i.e., isobutyl POSS) and UV-attenuating ones (i.e., ferrocene and 4-cyano-4′-biphenyl). This study expands the library of POSS-based shape amphiphiles with numerous possibilities for head manipulations, offering an important step toward new shape amphiphiles beyond traditional hydrophobic/hydrophilic nature for potential applications in giant molecule-based nanoscience and technology.
Head diversification of shape amphiphiles not only broadens the scope of supramolecular engineering for new self-organizing materials but also facilitates their potential applications in high technologies. In this letter, T10 azido-functionalized polyhedral oligomeric silsesquioxane (POSS) nanoparticle was used to construct new shape amphiphiles via sequential “click” chemistry for addressing two issues: (1) new symmetry of T10 POSS head could enrich the self-assembly behaviors of shape amphiphiles, and (2) copper-catalyzed azide–alkyne cycloaddition (CuAAC)-based head functionalization strategy allows the introduction of diverse functionalities onto POSS heads, including bulky ligands (i.e., isobutyl POSS) and UV-attenuating ones (i.e., ferrocene and 4-cyano-4′-biphenyl). This study expands the library of POSS-based shape amphiphiles with numerous possibilities for head manipulations, offering an important step toward new shape amphiphiles beyond traditional hydrophobic/hydrophilic nature for potential applications in giant molecule-based nanoscience and technology.