研究室工作进展 Jan 25th, 2011
研究室工作进展 January 25, 2011
One-Pot Selective Syntheses of 5-Azaindoles through Zirconocene-Mediated Multicomponent Reactions with Three Different Nitrile Components and One Alkyne Component
Shaoguang Zhang, Wen-Xiong Zhang, Jing Zhao and Zhenfeng Xi*
Chem. Eur. J. 2011, doi: 10.1002/chem.201003119
Three different nitriles in order: 5-Azaindoles either with three different substituents at their 2-, 4,- and 6-positions or with two identical substituents at their 2- and 6-positions and a different one at the 4-position were obtained in a perfectly chemo- and regioselective manner through a zirconocene-mediated multicomponent coupling process.