许言

学术简历:

• 2021.7- 伟德国际1946官网，特聘研究员，博士生导师， PI
• 2018-2021 加州理工学院，博士后 (合作导师：Prof. Robert H. Grubbs)
• 2013-2018 德州大学奥斯汀分校、芝加哥大学，博士 (导师：Prof. Guangbin Dong)
• 2009-2013伟德国际1946官网，本科学习（导师: 王剑波教授、张艳教授）

研究领域及兴趣：

本课题组的主要研究方向是基于催化策略创新并辅以新试剂开发的有机合成方法学。其中我们尤为感兴趣的内容包括针对常见化学结构开发非常见的连续或易位官能团化，新型碳氢及烯烃转化，以及复杂骨架的修饰和结构调整。我们的研究涉及过渡金属催化和光催化的前沿领域。 欢迎优秀学子报考博士研究生或参与本科生科研，同时面向国内外招聘博士后和研究助理，具体申请方式请见课题组主页和化学院招聘信息。

代表性论文：

1. Wang, Y.; Zhang, Z.; Xu, Y.*, "cis-Selective Acyclic Diene Metathesis Polymerization Using Bulky Cyclometalated Ruthenium Carbene Catalysts", Macromolecules 2023, 56, 9138 – 9145.
2. Chen, K.†; Zeng, Q.†; Xie, L.; Xue, Z.; Wang, J.; Xu. Y.* “Functional-group translocation of cyano groups by reversible C–H sampling”, Nature 2023, 620, 1007–1012.
3. Xu, Y.; Qi, X.; Zheng, P.; Berti, C. C.; Liu, P.; Dong, G. “Deacylative Transformations of Ketones via Aromatization-Promoted C−C Bond Activation”, Nature, 2019, 567, 373–378.
4. Xu, Y.; Gan, Q.; Samkian, A. E.; Ko, J. H.; Grubbs, R. H. “Bulky Cyclometalated Ruthenium Nitrates for Challenging Z-Selective Metathesis: Efficient One-Step Access to α-Oxygenated Z-Olefins from Acrylates and Allyl Alcohols”, Angew. Chem. Int. Ed., 2022, 61, e202113089.
5. Zhou, X.; Xu. Y.*; Dong, G*. “Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones”, J. Am. Chem. Soc. 2021, 143, 20042–20048. (*co-corresponding)
6. Zhou, X.; Xu. Y.*; Dong, G*.“Deacylation-Aided C–H Alkylative Annulation through C–C Cleavage of Unstrained Ketones”, Nat. Catal., 2021,4,703-710. (*co-corresponding) 
7. Xu, Y.; Wong, J. J.; Samkian, A. E.; Ko, J. H.; Chen, S.; Houk, K. N.; Grubbs, R. H. “Efficient Z-Selective Olefin-Acrylamide Cross-Metathesis Enabled by Sterically Demanding Cyclometalated Ruthenium Catalysts”, J. Am. Chem. Soc., 2020, 142, 20987–20993. 
8. Xu, Y.; Dong, G. “sp3 C–H Activation via Exo-type Directing Groups”, Chem. Sci., 2018, 9, 1424–1432. 
9. Xu, Y.; Young, M. C.; Dong, G. “Catalytic Coupling between Unactivated Aliphatic C–H Bonds and Alkynes via a Metal–Hydride Pathway”, J. Am. Chem. Soc., 2017, 139, 5716–5719.
10. Xu, Y. †; Young, M. C. †; Wang, C.; Magness, D.; Dong, G. “Catalytic C(sp3)–H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ”, Angew. Chem. Int. Ed., 2016, 55, 9084–9087.
11. Xu, Y.; Su, T.; Huang, Z.; Dong, G. “Practical Direct α-Arylation of Cyclopentanones by Palladium/Enamine Cooperative Catalysis”, Angew. Chem. Int. Ed., 2016, 55, 2559–2563.
12. Xu, Y. †; Yan, G. †; Ren, Z.; Dong, G. “Diverse sp3 C−H Functionalization through Alcohol β-Sulfonyloxylation", Nat. Chem., 2015, 7, 829-834. 
13. Samkian, A. E. †; Xu, Y. †; Virgil, S. C.; Yoon, K.-Y.; Grubbs, R. H. “Synthesis and Activity of Six-Membered Cyclic Alkyl Amino Carbene–Ruthenium Olefin Metathesis Catalysts”, Organometallics, 2020, 39, 495–499.