[PUBLICATIONS] Hu Yali Publishes a Paper in Biomaterials

Dec. 2020

To mitigate the high immunogenicity of asparaginase (ASNase), we used rigid helical zwitterionic polypeptides to modify ASNase and formed an urchin-like conjugate.

This conjugate showed significantly reduced immunogenicity as compared to a similarly made PEG-ASNase conjugate.

This is a nice collaboration work with the Lymphoma team from Peking University Cancer Hospital & Institute.

https://www.sciencedirect.com/science/article/pii/S0142961220308528?via=ihub